Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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6,376 – 6,390 of 6,672 results

6,376

Medchemexpress LLC 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy- | 485-47-2 | 100.0 % | 100 G

Ninhydrin is a chromogenic analytical probe used for the quantification of amino acids and proteins. It reacts with primary and secondary amines, producing a blue or purple reaction product, diketohydrindylidene-diketohydrindamine. It is utilized in the amino acid analysis of proteins; most amino acids, excluding proline, can be hydrolyzed and react with ninhydrin, after which they are colorimetrically quantified following chromatographic separation.

Chromogenic analytical probe.
Reacts with primary and secondary amines.
Solid appearance, white to light yellow color.
Quantification of amino acids and proteins.
Useful in amino acid analysis of proteins.

Pricing & Availability

6,377

Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 1 G

Eperisone hydrochloride is an orally active antispastic agent with a vasodilator effect. It is used for the research of muscle stiffness and pain. This compound is a potent and selective P2X7 receptor antagonist, also exhibiting antagonism for human P2X3. It works by relaxing both skeletal muscles and vascular smooth muscles, demonstrating several beneficial effects.

Reduces myotonia.
Improves circulation.
Suppresses the pain reflex.
Preferentially suppresses lung fibroblast activity.
Suppresses bleomycin-dependent pulmonary fibrosis.
Not toxic to alveolar epithelial cells in vitro.

Pricing & Availability

6,378

Medchemexpress LLC Imidapril (hydrochloride) | 89396-94-1 | MFCD00870777 | 99.9% | 100 MG

Imidapril hydrochloride (TA-6366) is an orally active inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. It works by suppressing the conversion of angiotensin I to angiotensin II, which in turn reduces total peripheral resistance and systemic blood pressure. It is used in research for hypertension, type 1 diabetic nephropathy, and chronic heart failure.

Orally active ACE and MMP-9 inhibitor
Suppresses conversion of angiotensin I to angiotensin II
Reduces total peripheral resistance and systemic blood pressure
Used in research for hypertension
Used in research for type 1 diabetic nephropathy
Used in research for chronic heart failure

Pricing & Availability

6,379

Medchemexpress LLC Lecozotan hydrochloride | 433282-68-9 | 98.7% | 520.02 | 5 MG

Lecozotan hydrochloride (SRA-333) hydrochloride is an orally active and selective antagonist of 5-HT1A with a Ki of 4.5 nM for cloned human 5-HT1A receptor. It enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. This product has the potential for mild-to-moderate Alzheimer's disease (AD) research.

Orally active and selective 5-HT1A antagonist.
Enhances the release of glutamate and acetylcholine in the hippocampus.
Possesses cognitive-enhancing properties.
Potential for mild-to-moderate Alzheimer's disease research.

Pricing & Availability

6,380

Medchemexpress LLC Sovesudil hydrochloride | 2984963-50-8 | 99.5% | 443.90 | 25 MG

Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. It lowers intraocular pressure (IOP) without inducing hyperemia.

Potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor
IC50s of 3.7 nM for ROCK-I and 2.3 nM for ROCK-II
Lowers intraocular pressure (IOP) without inducing hyperemia
Induces altered cellular behavior of human trabecular meshwork (HTM) cells in vitro
Effectively reduces IOP in ocular normotensive and acute hypertensive rabbits without causing distinct hyperemia in vivo

Pricing & Availability

6,381

Medchemexpress LLC Ponatinib hydrochloride | 1114544-31-8 | 99.8% | 569.02 | 25 MG

Ponatinib hydrochloride, also known as AP24534 hydrochloride, is an orally active multi-targeted kinase inhibitor. It inhibits various kinases with IC50s including 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src.

Purity of 99.76%
CAS number: 1114544-31-8
Molecular weight: 569.02
Appears as an off-white to light yellow solid
Soluble in DMSO at 25 mg/mL
Targets Bcr-Abl, FGFR, PDGFR, VEGFR, Src, and Autophagy pathways
Store at 4°C, sealed, away from moisture; in solvent, store at -80°C for 6 months or -20°C for 1 month

Pricing & Availability

6,382

Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 10MM 1ML

AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 10MM 1ML

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6,383

Medchemexpress LLC Cl-amidine hydrochloride | 1373232-26-8 | MFCD22201084 | 99.8% | 347.24 | C14H20Cl2N4O2 | 1 ML

Cl-amidine hydrochloride is an orally active peptidylarginine deiminase (PAD) inhibitor used in biochemical, cellular, and in vivo research to block protein citrullination and probe PAD-related pathways.

Inhibits PAD1, PAD3, and PAD4 with reported IC50 values of 0.8 μM, 6.2 μM, and 5.9 μM.
Available as a 10 mM solution in DMSO or as solid quantities for formulation flexibility.
High purity (~99.8%) suitable for biochemical and cellular assays.
Demonstrated activity in cell apoptosis and neutrophil extracellular trap formation assays.
Shows efficacy in murine models of colitis and sepsis in published studies.
Provided supporting documents: data sheet, SDS, COA, HNMR, RP-HPLC, and LCMS.

Pricing & Availability

6,384

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG

Melitracen hydrochloride is a research-grade tricyclic antidepressant hydrochloride salt supplied for laboratory use. It is used in pharmacological studies of monoamine neurotransmitter uptake and serotonergic (5-HT) receptor pathways. Provided as a solid for in vitro and preclinical research; not for human or veterinary use.

Tricyclic antidepressant hydrochloride salt.
Molecular formula C21H26ClN.
Molecular weight 327.89.
Purity >98.0% (HPLC).
Available as a solid powder, commonly in 200 MG quantities.
For research use only; not for human or veterinary use.

Pricing & Availability

6,385

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG

Azasetron hydrochloride is a benzamide derivative functioning as a potent and selective 5-HT3 receptor antagonist. It is utilized in studies concerning chemotherapy-induced nausea and vomiting (CINV).

Potent and selective 5-HT3 receptor antagonist
Used in studies for chemotherapy-induced nausea and vomiting (CINV)
Purity of 99.76%
Solid, white to off-white appearance
Effectively penetrates skin in in vivo studies
IC50 for 5-HT3 Receptor is 0.33 nM

Pricing & Availability

6,386

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 50 MG

Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent. It also reduces reactive oxygen species (ROS) production, increases mitochondrial DNA, and improves mitochondrial function.

Oral glucose-lowering agent
Reduces reactive oxygen species production
Increases mitochondrial DNA
Improves mitochondrial function

Pricing & Availability

6,387

Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG

Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to the estrogen receptor, and it also inhibits aromatase activity. It has potential for breast cancer study.

Key active metabolite of Tamoxifen (TAM).
Higher affinity and specificity to estrogen receptor.
Inhibits aromatase activity.
Potential for breast cancer study.
Approximately 100-fold more potent as an antagonist of the ER than tamoxifen.
Targets estrogen receptor α for degradation in breast cancer cells.
Blocks ERA transcriptional activity and inhibits estrogen-induced breast cancer cell proliferation.

Pricing & Availability

6,388

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG

Ansofaxine hydrochloride is a triple reuptake inhibitor designed to inhibit serotonin, dopamine, and norepinephrine reuptake. It demonstrates IC50 values of 723 nM, 491 nM, and 763 nM for these reuptake processes, respectively. This compound is intended for research use only.

Triple reuptake inhibitor
Inhibits serotonin, dopamine, and norepinephrine reuptake
Intended for research use only
Appears as a solid
Color ranges from white to off-white
Recommended storage for solid is 4°C, sealed and away from moisture
For solutions, store at -80°C for up to 6 months, or -20°C for 1 month

Pricing & Availability

6,389

Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.90% | 361.66 | 1 ML

SSR180711 hydrochloride is an orally active, selective, and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. It can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). This compound increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus.

Acts on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM).
Increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus.
Selective for the α7 receptor subtype compared to α4β2, α3β2, α3β4, and α1β1γδ human n-AChR subtypes.
Rapidly penetrates into the brain (ID50=8 mg/kg; p.o.).
Dose-dependently inhibits specific [3H]α-BTX binding in the mouse brain.
Dose-dependently increases extracellular acetylcholine (ACh) levels in the hippocampus and prefrontal cortex of freely moving rats.

Pricing & Availability

6,390

Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | MFCD28400873 | 99.3% | 299.84 | C16H26ClNO2 | 10 MG

Emixustat hydrochloride is a research-grade RPE65 inhibitor and visual cycle modulator used to study retinal physiology and degenerative eye diseases. It inhibits retinol isomerization with low-nanomolar potency (IC50 ~4.4 nM) and is supplied as a hydrochloride salt for stability; it is used in both in vitro and in vivo retinal research models.

Inhibits RPE65 with low-nanomolar potency.
Modulates the visual cycle to reduce retinol isomerization.
Suitable for in vitro and in vivo retinal research applications.
Supplied as a hydrochloride salt for improved handling and stability.
High purity by LCMS (reported >99%).
Available in small-mass packaging for dosing and preclinical studies.

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Alcohols and polyols

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Medchemexpress LLC 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy- | 485-47-2 | 100.0 % | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Imidapril (hydrochloride) | 89396-94-1 | MFCD00870777 | 99.9% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lecozotan hydrochloride | 433282-68-9 | 98.7% | 520.02 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sovesudil hydrochloride | 2984963-50-8 | 99.5% | 443.90 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ponatinib hydrochloride | 1114544-31-8 | 99.8% | 569.02 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cl-amidine hydrochloride | 1373232-26-8 | MFCD22201084 | 99.8% | 347.24 | C14H20Cl2N4O2 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.90% | 361.66 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | MFCD28400873 | 99.3% | 299.84 | C16H26ClNO2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More